Epidemiologic correlates of ovarian cortical inclusion cysts (CICs) support a dual precursor pathway to pelvic epithelial cancer
نویسندگان
چکیده
منابع مشابه
Pelvic inflammatory disease and the risk of epithelial ovarian cancer.
Infertility is a common complication of pelvic inflammatory disease (PID) and may result in decreased parity. Low parity and possibly infertility are risk factors for ovarian cancer. We therefore examined the association between ovarian cancer and history of PID in a case-control study conducted during 1989-1992 in metropolitan Toronto and nearby areas of Southern Ontario, Canada. In total, 450...
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Chronic ovulation as a contributing factor for the development of epithelial ovarian cancer in women has long been an outstanding hypothesis. To test the incessant ovulation hypothesis, mice were superovulated using weekly ip injections of pregnant mare serum gonadotropin (5 IU/animal), followed 48 h later by human chorionic gonadotropin (5 IU/animal). Wild-type CD1 mice were used along with CD...
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1Department of Oncology, Vejle Hospital, Kabbeltoft 25, 7100 Vejle, Denmark 2 Institute of Regional Health Services Research, University of Southern Denmark, 5230 Odense, Denmark 3Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, School of Medicine, New Haven, CT 06510, USA 4Department of Pathology, Vejle Hospital, 7100 Vejle, Denmark 5Department of Pathology, Yal...
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Epithelial ovarian cancer stem cells (EOC stem cells) have been associated with recurrence and chemoresistance. CD44 and CK18 are highly expressed in cancer stem cells and function as tools for their identification and characterization. We investigated the association between the number of CD44+ EOC stem cells in ovarian cancer tumors and progression-free survival. EOC stem cells exist as clust...
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ژورنال
عنوان ژورنال: Gynecologic Oncology
سال: 2009
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2009.06.032